Discussion
There is a reasonably strong consensus among scholars that leta’ah refers to the lacertid and agama lizards, both of which are common and fairly obvious in Israel. The lacertids are soft-skinned lizards that live in close proximity to roads and houses. One of the more colorful is the Syrian Green Lizard Lacerta trilineata, which lives in orchards and woods. The most common of the agamas is the Rainbow Agama Agama stellio, which is very common around houses and on walls and rocks.
Most scholars agree that tsav is the name for the dab or thorn-tailed lizards of which there are many species in Israel. Two of the most common are the Egyptian Thorn-tailed Lizard Uromastyx aegyptia and the Colored Thorn-tailed Lizard Uromastyx ornata. The name “dab” is an English version of their Arabic name dhubb or dhabb, which is reflected in the Hebrew tsav.
Description
Lacertid lizards (leta’ah) are fairly small, about 15–20 centimeters (6–8 inches) long, and they have a shiny smooth skin. Syrian green lizards have dark green spots on a lighter green background, with a yellow-green belly. They feed on flies, gnats, mosquitoes, and ants.

The thorn-tailed lizards (tsav) are relatively large desert lizards with a length of about 65 centimeters (26 inches). They have a fairly thick, squat appearance and have a thick short tail covered with sharp spikes, which are actually cone-shaped scales. They use this tail for defense. They often crawl into holes or cracks in rocks and then block the entrance with their thorny tail. They are vegetarian, eating various succulent desert plants. Even though they are on the list of unclean foods, they are commonly eaten by Arabs and Bedouin, who keep them in cages and fatten them.
Special significance or symbolism
They are listed as unclean.
Translation

For tsav a phrase, such as “big thorny lizard” or “big lizard with a thorny tail", is usually the best option. Where languages differentiate between smaller lizards and monitor lizards, “thorny monitor” or “monitor with a thorny tail” will better convey the idea of large size.